A novel pathogenic classification of cancers - ENS - École normale supérieure Accéder directement au contenu
Article Dans Une Revue Cancer Cell International Année : 2014

A novel pathogenic classification of cancers


According to contemporary epidemiological and experimental evidence, we propose a novel classification of cancers based on pathogenesis instead of classifications based on histological appearance of cancer. This new scheme first defines cancers as either 1. inborn errors of development or 2. sporadic ones, and then sub-defines the former into 1A. inborn inherited errors of development, being those due to mutations contributed by one or both parents' gametes to the developing conceptus, and 1B. inborn induced errors of development when the malformations and/or cancers are due to environmental carcinogenic exposure during pregnancy. It is anticipated that the origin of an increasing number of so-called sporadic cancers will turn out to be linked to the inborn induced errors of development group.
Fichier principal
Vignette du fichier
Sonnenschein2014_Article_ANPC.pdf (388.44 Ko) Télécharger le fichier
Origine : Publication financée par une institution

Dates et versions

hal-03575041 , version 1 (15-02-2022)





Carlos Sonnenschein, Barbara Davis, Ana M. Soto. A novel pathogenic classification of cancers. Cancer Cell International, 2014, 14 (1), pp.113. ⟨10.1186/s12935-014-0113-9⟩. ⟨hal-03575041⟩
3 Consultations
9 Téléchargements



Gmail Facebook Twitter LinkedIn More